Parkinson’s Disease is the second most common neurodegenerative disorder in the aging population. It is associated with progressive loss of nigrostriatal dopaminergic neurons. Parkinsonism is a clinical syndrome that consists of motor and non-motor symptoms. It has been well described that many if not all of these deficits are associated with abnormalities related to the neurotransmitter Dopamine. This review is intended for primary care physicians who often establish the diagnosis and initiate Parkinson’s treatments. One challenge faced by the primary care physician is to decide the appropriate medication and starting dose. Often medications are used at very low doses or incorrect dosing schedules This review aims to summarize these medications, their potential side effects and the rationale for medication choices.
Conflict(s) of Interest
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Musey, Conrad and Shivkumar, Vikram
"Medical therapies for motor symptoms in Parkinson’s Disease,"
Marshall Journal of Medicine:
4, Article 13.
Available at: http://mds.marshall.edu/mjm/vol3/iss4/13