Marshall Digital Scholar

Title

Application of Poly(amidoamine) Dendrimers for Use in Bionanomotor Systems

Authors

Madhukar Babu Kolli, Marshall UniversityFollow
B. Scott Day, Marshall UniversityFollow
Hideyo Takatsuki, Marshall University
Siva Krishna Nalabotu, Marshall UniversityFollow
Kevin M. Rice, Marshall UniversityFollow
Kazuhiro Kohama, Marshall University
Murali K. Gadde, Marshall UniversityFollow
Anjaiah Katta, Marshall UniversityFollow
Eric R. Blough, Marshall UniversityFollow

Document Type

Article

Publication Date

5-4-2010

Abstract

The study and utilization of bionanomotors represents a rapid and progressing field of nanobiotechnology. Here, we demonstrate that poly(amidoamine) (PAMAM) dendrimers are capable of supporting heavy meromyosin dependent actin motility of similar quality to that observed using nitrocellulose, and that microcontact printing of PAMAM dendrimers can be exploited to produce tracks of active myosin motors leading to the restricted motion of actin filaments across a patterned surface. These data suggest that the use of dendrimer surfaces will increase the applicability of using protein biomolecular motors for nanotechnological applications.

Comments

Reprinted with permission from Kolli, M. B., Day, B. S., Takatsuki, H., Nalabotu, S. K., Rice, K. M., Kohama, K., ... & Blough, E. R. (2010). Application of poly(amidoamine) dendrimers for use in bionanomotor systems. Langmuir, 26(9), 6079-6082. http://pubs.acs.org/doi/abs/10.1021/la100174h

Copyright 2010 American Chemical Society

Recommended Citation

Kolli, M. B., Day, B. S., Takatsuki, H., Nalabotu, S. K., Rice, K. M., Kohama, K., ... & Blough, E. R. (2010). Application of poly(amidoamine) dendrimers for use in bionanomotor systems. Langmuir, 26(9), 6079-6082.