Understanding the Burden of Osteoporosis and Use of the World Health Organization FRAX

Franklin D. Shuler MD, PhD, Marshall University
Jacob Conjeski MD, University of South Florida
David Kendall
Jonathon Salava MD, Marshall University

Copyright 2012, SLACK Incorporated.

doi: 10.3928/01477447-20120822-12


Fracture prevention is a critical component of managing osteoporosis, which is no longer defined by T-score alone. The internationally validated World Health Organization Fracture Risk Assessment Tool (FRAX) provides the clinician a state-of-the-art tool for predicting patients at greatest risk for fracture. The FRAX tool takes into account country, bone mineral density of the hip (when available), age, sex, and 8 clinical risk factors to calculate the 10-year probability of a major osteoporotic fracture and the 10-year probability of a hip fracture. From this tool, an absolute fracture risk is generated, aiding clinicians in determining which patients with low bone mass and osteoporosis to treat.