Dapsone, Methemoglobinemia, Intravascular Hemolysis.
Medicine and Health Sciences
Dapsone is a Leprostatic agent routinely used for Malaria, Leprosy and as a prophylaxis for Pneumocystis jiroveci pneumonia (PCP), as well as Toxoplasma gondii in immunocompromised patients. Methemoglobinemia is an adverse effect of dapsone which can be life-threatening. Detailed is a case of dapsone-induced methemoglobinemia in a young woman with lupus nephritis treated with chronic immunosuppressant medications.
Al Sanani, MD, Ahlim
"The Role of Arterial Blood Gas in Distinction of Intravascular Hemolysis in a Patient with Lupus Nephritis.,"
Marshall Journal of Medicine:
3, Article 6.
Available at: https://mds.marshall.edu/mjm/vol2/iss3/6