Na/K-ATPase amplification of oxidant stress; a universal but unrecognized clinical target?
Description
Schematic showing Na/K‐ATPase as reactive oxygen species (ROS) amplifier system. CTS‐cardiotonic steroids, Orange dimer is Na/K‐ATPase. pNaKtide refers to peptide formed from epitope of Na/K‐ATPase a1 subunit known to bind Src tyrosine kinase fused with TAT leader sequence.