Randomized Vitamin D Supplementation in Vitamin D Deficient Obese Children from West Virginia
Objective: Vitamin D (Vit D) deﬁciency is a very common problem in obese children, but clinical guidelines for maintenance or treatment have not been published for this population. The aim was to assess the beneﬁt of 2 months Vit D supplementation given to deﬁcient obese children from WV.
Design: Vit D deﬁcient obese children were prospectively recruited. Exclusion criteria included <8 years, and medical conditions that may affect Vit D homeostasis. Participants were randomized into two supplement groups: 5,000IU/day (Group A) or 50,000IU/week (Group B). Serum 25(OH)D levels were measured at baseline and post-treatment.
Results: Sixty obese children were screened of whom 39 (65%) were deﬁcient (<20ng/ml). Of the 39 recruited, 26 completed the study. The mean serum 25(OH)D after 2 months treatment were signiﬁcantly higher in Group B (p= 0.02), but most reached normal levels (>30ng/ml).
Conclusions: Two months Vit D supplementation (5000IU/day or 50,000IU/week) was suﬃcient to normalize 25(OH)D levels in Vit D deﬁcient obese West Virginian children.
Elitsur Y, Preston DL (2016) Randomized Vitamin D Supplementation in Vitamin D Deficient Obese Children from West Virginia. Arch Clin Gastroenterol 2(1): 065-068. DOI: http://doi.org/10.17352/2455-2283.000024