Document Type
Article
Publication Date
4-2000
Abstract
A549 xenografts were allowed to grow in nude mice to about 5 mm in diameter, then diets were changed to modified AIN-76 diets containing 19% wt/wt. fish oil (FO) or 20% wt./wt. com oil (CO). Ten days later dietary ferric citrate (0.3% wt./dry wt.) was added and doxoribicin (DOX) treatment (3.6 mg/kg i.v. each of the 5 days for 18 days) commenced. Treatment with DOX halted the growth of tumors in the CO fed mice. However, in those mice, which consumed FO or FO with ferric citrate, treatment with DOX caused significant tumor regression.
Recommended Citation
Hardman, W. E., Moyer, M. P. & Cameron, I. L. (2000) Dietary fish oil sensitizes A549 lung xenografts to doxorubicin chemotherapy. Cancer Letters. 151:145-151.
erratum
Included in
Biochemical Phenomena, Metabolism, and Nutrition Commons, Medical Microbiology Commons, Oncology Commons
Comments
Reprinted from Cancer Letters, 151/2, Hardman, W. E., Moyer, M. P. & Cameron, I. L., Dietary fish oil sensitizes A549 lung xenografts to doxorubicin chemotherapy, 145-151, 2000, with permission from Elsevier. http://dx.doi.org/10.1016/S0304-3835(99)00396-1
© 2000 Elsevier Science Ireland Ltd. All rights reserved.