We read the article by Miguel et al1 regarding Purtscher’s and Purtscher-like retinopathies with great interest. As the authors well describe, ‘Purtscher-like retinopathy’ is diagnosed in patients with fundus findings similar to Purtscher’s retinopathy, without a history of trauma but with known systemic associations.1 Current proposed mechanisms for the underlying pathogenesis include leukocyte aggregation by activated complement factor 5 (C5a).2 As noted by the authors’ systematic review, there is currently no established treatment for Purtscher-like retinopathy, although the literature consists of several case reports of treatment with corticosteroids, without certainty as to effect on the clinical course.1 Herein, we report for the first time a case of Purtscher-like retinopathy treated successfully with intravitreal bevacizumab injection.
Nesmith B, Bitar MS, Schaal S. The anatomical and functional benefit of bevacizumab in the treatment of macular edema associated with purtscher-like retinopathy. Eye. 2014;28:1038-1040. http://dx.doi.org/10.1038/eye.2014.85