Title
Hyperammonemia Associated With Valproic Acid Use in Elderly Psychiatric Patients
Document Type
Article
Publication Date
7-1-2012
Abstract
Valproic acid (VPA) is associated with hyperammonemia; however, little is known about this phenomenon in the geriatric psychiatric population. Of 12 such patients prescribed VPA, 83.3% had elevated ammonia. This occurred in the absence of elevated liver enzymes, and there was no association of VPA serum-level to hyperammonemia.
Recommended Citation
Holroyd S, Overdyke JT. Hyperammonemia associated with valproic acid use in elderly psychiatric patients. The Journal of Neuropsychiatry and Clinical Neurosciences. 2012 Jul;24(3):372-4.
Comments
The version of record is available from the publisher at https://doi.org/10.1176/appi.neuropsych.10100151.
Copyright © 2012 American Psychiatric Association.