Date of Award

2019

Degree Name

Chemistry

College

College of Science

Type of Degree

M.S.

Document Type

Thesis

First Advisor

Dr. Michael Norton, Committee Chairperson

Second Advisor

Dr. Bin Wang

Third Advisor

Dr. Scott Day

Abstract

Carbon nanotubes1 are cylindrical carbon molecules and can be considered to be composed of one atom thick sheets of carbon called graphene. They have been at the forefront of nanochemistry due to their strength and multiple properties such as absorption, fluorescence, semiconduction, and light scattering capability. DNA Origami (DO)2 has emerged as a novel domain for molecular design, resulting in the generation of numerous one, two, and three-dimensional structures that have provided platforms for the organization of organic species and inorganic nanoparticles through simple modifications. The use of DNA Origami to control the placement of single walled carbon nanotubes (SWCNT) with precise alignment,3 purity and length would be a significant advance in controlled nanoscale organization.4 G-quadruplex (G4) secondary structures are guanine rich ssDNA sequences which fold to create square planar guanine tetrads.5 When G4 is introduced to Hemin, a (G4)/hemin-based DNA enzyme (DNAzyme) self assembles and possesses horseradish peroxidase (HRP)-mimicking catalytic properties.6 In this work, multiple approaches for the immobilization of SWCNTs at precisely designated locations on cross shaped DNA origami7 were implemented, and the results interpreted.

Subject(s)

Carbon nanotubes.

Graphene.

Nanotubes.

DNA -- Structure.

Available for download on Friday, August 27, 2021

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