Pulmonary alveolar microlithiasis diagnosed with radiography, CT, and bone scintigraphy

Authors

Emad Alkankan, Marshall UniversityFollow
Hasan Yamin, Marshall UniversityFollow
Hazim Bukamur, Marshall UniversityFollow
Fadi Alkhankan, Marshall UniversityFollow
Yousef Shweihat, Marshall UniversityFollow
Fuad Zeid, Marshall UniversityFollow

Document Type

Article

Publication Date

6-1-2019

Abstract

Pulmonary alveolar microlithiasis is rare disease characterized by accumulation of calcium phosphate microlithis in the alveoli. The pathogenesis relates to mutation in the gene SLC34A2 (solute carrier family 34 member 2) located on chromosome 4p15.2, which produces a defective sodium-phosphate cotransporter in alveolar epithelial type-2 cells, making these cells unable to clear phosphorus released during recycling of surfactant.

Comments

Copyright © 2019 The Authors. Published by Elsevier Inc. on behalf of University of Washington. This is an open access article under the CC BY-NC-ND license. (http://creativecommons.org/licenses/by-nc-nd/4.0/)

Recommended Citation

Alkhankan E, Yamin H, Bukamur H, Alkhankan F, Shweihat Y, Zeid F. Pulmonary alveolar microlithiasis diagnosed with radiography, CT, and bone scintigraphy. Radiology case reports. 2019 Jun 1;14(6):775-7.