Hepatocellular Carcinoma As Unusual Cause for Paraplegia
Hepatocellular carcinoma (HCC) is the dominant form of primary liver cancer. Approximately 70% to 90% of patients with HCC have chronic liver disease and cirrhosis; major risk factors include hepatitis B virus, hepatitis C virus, alcoholic liver disease, and nonalcoholic steatohepatitis. The most common sites of metastases from HCCinclude the lung, lymph nodes, and portal vein, whereas involvement of the bone is rare. Spinal cord compression (SCC) is an unusual presentation for HCC metastases. Here we describe a patient with HCC who presented with SCC.
Khaled Ali Sherif, Wesam Frandah, Suzanne Graham, and Michael Phy. Hepatocellular Carcinoma As Unusual Cause for Paraplegia. Journal of Clinical Oncology 2012 30:31, e303-e305.