Marshall Digital Scholar

Title

"Aligned-to-random’’ Nanofiber Scaffolds for Mimicking the Structure of the Tendon-to-Bone Insertion Site

Authors

Jingwei Xie, Marshall UniversityFollow
Xiaoran Li
Justin Lipner
Cionne N. Manning
Annie G. Schwartz
Stavros Thomopoulos
Younan Xia

Document Type

Article

Publication Date

6-2010

Abstract

We have demonstrated the fabrication of “aligned-to-random” electrospun nanofiber scaffolds that mimic the structural organization of collagen fibers at the tendon-to-bone insertion site. Tendon fibroblasts cultured on such a scaffold exhibited highly organized and haphazardly oriented morphologies, respectively, on the aligned and random portions.

Comments

Xie J., Li X., Lipner J., Manning C.N., Schwartz A.G., Thomopoulos, S. et al. "Aligned-to-random” nanofiber scaffolds for mimicking the structure of the tendon-to-bone insertion site. Nanoscale, 2 (6) (2010), pp. 923–926. DOI: 10.1039/C0NR00192A

Reproduced by permission of The Royal Society of Chemistry

© Royal Society of Chemistry 2012

Recommended Citation

Xie J., Li X., Lipner J., Manning C.N., Schwartz A.G., Thomopoulos, S. et al. "Aligned-to-random” nanofiber scaffolds for mimicking the structure of the tendon-to-bone insertion site. Nanoscale, 2 (6) (2010), pp. 923–926.