Title
Pseudomonas aeruginosa MucD Regulates the alginate Pathway through Activation of MucA Degradation via MucP Proteolytic Activity
Document Type
Article
Publication Date
1-2011
Abstract
Alginate overproduction in Pseudomonas aeruginosa can be caused by the proteolysis of the anti-sigma factor MucA regulated by the AlgW protease. Here, we show that inactivation of MucD, an HtrA/DegP homolog and alginate regulator, can bypass AlgW, leading to an atypical proteolysis of MucA that is dependent on the MucP protease.
Recommended Citation
Damron, F. H., & Yu, H. D. (2011, January). Pseudomonas aeruginosa MucD Regulates the Alginate Pathway through Activation of MucA Degradation via MucP Proteolytic Activity. Journal of Bacteriology, 193(1), 286-291.
Comments
This article was published in Journal of Bacteriology, 2011 January; 193(1): 286–291.
Published online 2010 October 29. doi: 10.1128/JB.01132-10
Publisher: author can archive post-print.