Date of Award

2024

Degree Name

Management Practice in Nurse Anesthesia

College

College of Business

Type of Degree

D.N.A.P.

Document Type

Research Paper

First Advisor

Alberto Coustasse, Dr.PH. MD, MBA, MPH

Second Advisor

Cassandra L. Taylor, DNP, DMP, APRN, CRNA

Abstract

The study reviewed several retrospective cohort studies that examined the impact of propofol-based total intravenous anesthesia (TIVA) versus volatile anesthesia (VA) on the long-term survival of colorectal cancer (CRC) surgery patients. Eight studies found no significant difference in mortality between the two anesthesia types, while three studies indicated a significant decrease in all-cause mortality favoring propofol TIVA. The studies had varying follow-up periods, with some extending to five years. Notably, two studies controlled the type of volatile anesthetic used, specifically sevoflurane and desflurane. The findings suggest a potential survival advantage for propofol TIVA, warranting further investigation.

Subject(s)

Health services administration.

Intravenous anesthesia.

Anesthesia -- Cancer.

Inflammation -- Prevention -- Treatment.

Metastasis.

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