Author Credentials

Tyler Bayliss, BS Caleb Clark, BS Errington C. Thompson, MD, FACS, FCCM

Author ORCID Identifier

Errington C. Thompson

Tyler Bayliss

Caleb Clark


colon, Ogilvie, Ogilvie's Syndrome, Acute Colonic Pseudoobstruction, colonoscopy, neostigmine


Gastroenterology | Internal Medicine | Medical Pharmacology | Medical Physiology | Medicine and Health Sciences | Obstetrics and Gynecology | Surgery


Ogilvie's syndrome (acute colonic pseudoobstruction) was first described in 1948. Acute colonic pseudoobstruction can occur in a variety of clinical settings, including postsurgical, obstetrics, pelvic surgery, critical care and sepsis. Clinicians need to recognize the syndrome early. Colonic distention without evidence of obstruction can be seen on plain films of the abdomen or CT scan. Successful therapies, including bowel rest, neostigmine and colonoscopic decompression, have been used. Avoiding respiratory compromise from abdominal distention and colonic perforation of the primary goals of treatment. Surgical intervention should be reserved for patients who are refractory to medical treatment or develops signs and symptoms of colonic ischemia or perforation.