A Review of Mesenchymal Stem Cell Injections for Osteoarthritis

Authors

Ammar Qureshi, Marshall UniversityFollow
Jill Goodwin, University of Arizona- College of Medicine PhoenixFollow
Franklin D. Shuler, Marshall UniversityFollow
Timothy Wilson-Byrne, Marshall University Joan C. Edwards School of MedicineFollow
John J. Jasko, Marshall UniversityFollow
Charles Giangarra, Marshall University Joan C. Edwards School of MedicineFollow

Author Credentials

Charles Giangarra MD Jill Goodwin MD Franklin D. Shuler MD Timothy Wilson-Byrne MD John J. Jasko MD Ammar Qureshi MD

Keywords

stem cells, osteoarthritis, review

Disciplines

Orthopedics | Podiatry | Primary Care

Abstract

Mesenchymal stem cell (MSC) injections for osteoarthritis is reviewed.

Methods- PubMed search identifying articles in English from 2003-2018 that used intra- articular injection (IA), cartilage repair, cartilage regeneration, chondral injury, adipose stem cells, bone marrow stem cells, mesenchymal stem cells, or autologous stem cells.

Results – 388 patients receiving IA MSC injections are discussed with data obtained from 10 case reports or case series, 4 randomized clinical trials (RCT), 1 cohort study, and 3 case controlled therapeutic studies.

Conclusions – MSC injections may be an effective adjunct in the management of osteoarthritis and a variety of cartilage related pathologies.

Recommended Citation

Qureshi A, Goodwin J, Shuler FD, Wilson-Byrne T, Jasko JJ, Giangarra C. A Review of Mesenchymal Stem Cell Injections for Osteoarthritis. Marshall J Med. 2018; 4(2): 46 DOI: