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Author Credentials

Kevat B. Patel MD Rita H. Hawarny MD Elizabeth Saunders MD Marc Hettlinger MD Niru Nahar MD

Keywords

Sarcomatoid Carcinoma, Primary Hepatic Sarcomatoid Carcinoma, Hepatocellular Carcinoma

Disciplines

Hematology | Hepatology | Internal Medicine | Medicine and Health Sciences | Oncology

Abstract

Sarcomatoid carcinoma is a rare malignant tumor of unknown pathogenesis characterized by poorly differentiated carcinoma tissue containing sarcoma-like differentiation of either spindle or giant cell and rarely occurs in the gastrointestinal tract and hepatobiliary-pancreatic system.1 Primary hepatic sarcomatoid carcinoma accounts for only 0.2 % of primary malignant liver tumors, and 1.8% of all surgically resected hepatocellular carcinomas.2 The majority of hepatic sarcomatoid carcinoma cases appear to occur simultaneously with hepatocellular or cholangiocellular carcinoma.3 The preferred treatment for hepatic sarcomatoid carcinoma is surgical resection and the overall prognosis is poor.4 This case depicts a 62-year-old female whom underwent initial resection in 2010 of a cavernous hemangioma. Seven years after her initial diagnosis she developed what was initially felt to be local recurrence of the hemangioma but additional diagnostic workup with a liver biopsy confirmed primary hepatic sarcomatoid carcinoma.

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