Wilson's disease, depression, suicidal ideation, neurogenetics, copper metabolism, neurologic Wilson's disease, hepatic, tremor in teenager
Digestive System Diseases | Genetic Phenomena | Hepatology | Medical Genetics | Medical Pathology | Medicine and Health Sciences | Nervous System Diseases | Neurology | Other Mental and Social Health | Psychiatry
Wilson’s Disease, a rare autosomal recessive genetic disease, is caused by a mutation in the ATP7B enzyme gene. Without this enzyme, copper builds up in the brain, liver, and cornea causing a multitude of symptoms. It is important to consider Wilson’s disease because the prognosis is dependent on timely diagnosis. This is an interesting case of a 19-year-old male who presented with suicidal thoughts and rapid weight loss. After many months and an extensive work-up, Wilson’s Disease was diagnosed. Due to his rapid decline, he was transferred to a larger university healthcare center where he is currently enrolled in clinical trial for WTX101.
Irvin, Sarah and McCarthy, Ryan
"Acute Diagnosis of Wilson’s Disease in a Teenage Patient,"
Marshall Journal of Medicine:
4, Article 3.
Available at: https://mds.marshall.edu/mjm/vol5/iss4/3
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