Diabetic Muscle Infarction: A Rare End-Organ Vascular Complication of Diabetes

Authors

Callie Seaman, Joan C. Edwards SOM, Marshall UniversityFollow
Michael Amos, Joan C. Edwards SOM, Marshall UniversityFollow
Adam M. Franks, Joan C. Edwards SOM, Marshall UniversityFollow
Asher Sexton, Joan C. Edwards SOM, Marshall UniversityFollow
Kimberly McClelland, Joan C. Edwards SOM, Marshall UniversityFollow
Erika M. Harris, Joan C. Edwards SOM, Marshall UniversityFollow

Author Credentials

Callie Seaman BS Michael Amos MD Adam M. Franks MD Asher Sexton MD Kimberly McClelland MD, MPH, MBA Erika M. Harris MD

Keywords

Diabetic Muscle Infarction, Diabetic Myonecrosis

Disciplines

Medicine and Health Sciences

Abstract

Diabetic muscle infarction (DMI) is a rare microvascular complication of spontaneous ischemic necrosis of skeletal muscle in patients with poorly controlled diabetes. We herein describe the case of a 26-year-old woman with a history of type I diabetes and accompanying diabetic microvascular complications of neuropathy, nephropathy and retinopathy, who presented with sudden onset of swelling and sharp pain in her bilateral thighs. T2-weighted MRI imaging revealed subcutaneous edema and sub-fascial, hyper-intense enhancement of proximal thigh musculature. DMI has a relatively non-specific clinical presentation; therefore, physician awareness is key for early diagnosis, as aggressive management has been associated with poor patient outcomes. With poor long-term prognosis and high reoccurrence, DMI acts as an indicator of vascular end-organ damage.

Recommended Citation

Seaman C, Amos M, Franks AM, Sexton A, McClelland K, Harris EM. Diabetic Muscle Infarction: A Rare End-Organ Vascular Complication of Diabetes. Marshall J Med. 2019; 5(4): 28 DOI: https://doi.org/10.33470/2379-9536.1232.