Date of Award
2024
Degree Name
Biomechanics
College
College of Health Professions
Type of Degree
M.S.
Document Type
Thesis
First Advisor
Dr. Suzanne Konz, Committee Chairperson
Second Advisor
Dr. Steven Leigh
Third Advisor
Dr. Holly Cyphert
Abstract
This study aimed to assess the effects of whole-body vibration (WBV) on the brain through changes in blood protein concentrations, seat and head accelerations, and symptomatology over time. Subjects were assigned to control, 1-hour, or 8-hour vibration exposure groups. Glial fibrillary acidic protein (GFAP) and S100B concentrations were measured. Root mean square average weighted vibration (Aws), vibration dose value (VDV), and seat-to-head transmissibility (STHT) were calculated. There were no differences in GFAP (p = 0.79) or S100B (p = 0.97) concentrations between 1-hour and 8-hour subjects (p = 0.79). Average weighted head acceleration (p = 0.566) and VDV (p = 0.843) were not significantly different between the 1- hour and 8-hour groups. The average resultant STHT was not significantly different across time (p = 0.852). Similarities in blood biomarker concentrations and head acceleration measures between exposure groups indicate that injury does not occur from singular WBV exposure. This study furthers the knowledge of heavy vehicle operation, demonstrating that individual exposure to WBV likely does not cause neurological injury.
Subject(s)
Biomechanics.
Blood proteins.
Recommended Citation
Miller, Nicholas, "Inflammatory protein elicitation in response to whole-body vibration exposure" (2024). Theses, Dissertations and Capstones. 1869.
https://mds.marshall.edu/etd/1869