Submissions from 2025
Zika virus impairs autophagic flux in trabecular meshwork, and inhibition of autophagy restricts ocular viral transmission and associated pathology, Faraz Ahmad, Prince Kumar, Pallav Singh, Trupti Joshi, and Pawan Kumar Singh
Disruption of the Placenta–Brain Axis in Transgenic Mice Lacking Serotonin Transporter (SERT) in Trophoblast Cells, David T. Ellenberger, Zhen Lyu, Rosalind T. B. Herrington, Jessica A. Kinkade, Gustavo W. Leone, Ji Ying Sze, Nathan J. Bivens, R. Frank Baker, R. Michael Roberts, Trupti Joshi, and Cheryl S. Rosenfeld
IRnet: Immunotherapy response prediction using pathway knowledge-informed graph neural network, Yuexu Jiang, Manish Sridhar Immadia, Duolin Wang, Shuai Zeng, Yen On Chan, Jing Zhou, Dong Xu, and Trupti Joshi
Childhood Asthma Biomarkers Derived from Plasma and Saliva Exosomal miRNAs, Abdelnaby Khalyfa, Mohit Verma, Meghan M. Alexander, Zhuanhong Qiao, Tammy Rood, Ragini Kapoor, Trupti Joshi, David Gozal, and Benjamin D. Francisco
Enhanced cell aggregation in the Chlamydomonas reinhardtii rbo 1 mutant in response to multifactorial stress combination, Lidia S. Pascual, Devasantosh Mohanty, Ranjita Sinha, Thi Thao Nguyen, Linda Rowland, Zhen Lyu, Trupti Joshi, Brian P. Mooney, Aurelio Gómez-Cadenas, Felix B. Fritschi, Sara I. Zandalinas, and Ron Mittler
G2PDeep-v2: A Web-Based Deep-Learning Framework for Phenotype Prediction and Biomarker Discovery for All Organisms Using Multi-Omics Data, Shuai Zeng, Trinath Adusumilli, Sania Zafar Awan, Manish Sridhar Immadi, Dong Xu, and Trupti Joshi
Factors underlying a latitudinal gradient in the S/G lignin monomer ratio in natural poplar variants, Jin Zhang, Pradeep Kumar Prabhakar, Yen On Chan, Rachel A. Weber, Mengjun Shu, Ganesh Panzade, Connor J. Cooper, Russell B. Davidson, Jin-Gui Chen, Sara S. Jawdy, Jerry M. Parks, Breeanna R. Urbanowicz, Gerald A. Tuskan, Trupti Joshi, Richard A. Dixon, Wellington Muchero, and Jaime Barros
Submissions from 2024
A multi-omics approach reveals a link between ribosomal protein alterations and proteome rebalancing in Arabidopsis thaliana seeds, Clement Bagaza, Huda Afnsa, Abou Yobi, Yen On Chan, Marianne L. Slaten, Kirk Czymmek, Trupti Joshi, Ron Mittler, Thomas P. Mawhinney, Dan H. Cohen, Hagai Yasuor, and Ruthie Angelovici
Development of a Standardized Soybean Cyst Nematode Screening Assay in Pennycress and Identification of Resistant Germplasm, Pawan Basnet, Clinton G. Meinhardt, Bishnu Dhital, Alice Nguyen, Jason D. Gillman, Trupti Joshi, Melissa G. Mitchum, and Andrew M. Scaboo
Natural and artificial selection of multiple alleles revealed through genomic analyses, Jana Biová, Ivana Kaňovská, Yen On Chan, Manish Sridhar Immadi, Trupti Joshi, Kristin Bilyeu, and Mária Škrabišová
PAI-1 Regulates the Cytoskeleton and Intrinsic Stiffness of Vascular Smooth Muscle Cells, Hekmat B. Khoukaz, Manisha Vadali, Alex Schoenherr, Francisco I. Ramirez-Perez, Mariana Morales-Quinones, Zhe Sun, Shumpei Fujie, Christopher A. Foote, Zhen Lyu, Shuai Zeng, Marc A. Augenreich, Dunpeng Cai, Shi-You Chen, Trupti Joshi, Yan Ji, Michael A. Hill, Luis A. Martinez-Lemus, and William P. Fay
Small and Long Non-Coding RNA Analysis for HumanTrophoblast-Derived Extracellular Vesicles and Their Effect on the Transcriptome Profile of Human Neural Progenitor Cells, Jessica A. Kinkade, Pallav Singh, Mohit Verma, Teka Khan, Toshihoko Ezashi, Nathan J. Bivens, R. Michael Roberts, Trupti Joshi, and Cheryl S. Rosenfeld
Effects of oxycodone on placental lineages: Evidence from the transcriptome profile of mouse trophoblast giant cells, Zhen Lyua, Jessica A. Kinkadeb, Nathan J. Bivens, R. Michael Roberts, Trupti Joshi, and Cheryl S. Rosenfeld
Enabling Cross-Modality Translation between Single-Cell RNA-Seq and Single-Cell ATAC-Seq through Web-Based Portal, Zhen Lyu, Sabin Dahal, Shuai Zeng, Juexin Wang, Dong Xu, and Trupti Joshi
Abnormal Morphology and Synaptogenic Signaling in Astrocytes Following Prenatal Opioid Exposure, Ethan B. Niebergall, Daron Weekley, Anna Mazur, Nathan A. Olszewski, Kayla M. DeSchepper, N. Radant, and Aishwarya S. Vijay
Employing Multi-Omics Analyses to Understand Changes during Kidney Development in Perinatal Interleukin-6 Animal Model, Ganesh Panzade, Tarak Srivastava, Daniel P. Heruth, Mohammad H. Rezaiekhaligh, Jianping Zhou, Zhen Lyu, Mukut Sharma, and Trupti Joshi
Anti-EGFR aptamer exhibits direct anti-cancer effects in NSCLC cells harboring EGFR L858R mutations, Brian J. Thomas, Sania Z. Awan, Trupti Joshi, Mark A. Daniels, David Porciani, and Donald H. Burke
Submissions from 2023
Genomic Variations Explorer (GenVarX): A Toolset for Annotating Promoter and CNV Regions Using Genotypic and Phenotypic Differences, Yen On Chan, Jana Biová, Anser Mahmood, Nicholas Dietz, Kristin Bilyeu, Mária Škrabišová, and Trupti Joshi
The Allele Catalog Tool: a web-based interactive tool for allele discovery and analysis, Yen On Chan, Nicholas Dietz, Shuai Zeng, Juexin Wang, Sherry Flint-Garcia, M. Nancy Salazar-Vidal, Mária Škrabišová, Kristin Bilyeu, and Trupti Joshi
Multi-Omics Analysis of Circulating Exosomes in Adherent Long-Term Treated OSA Patients, Abdelnaby Khalyfa, Jose M. Marin, David Sanz-Rubio, Zhen Lyu, Trupti Joshi, and David Gozal
Rapid Systemic Responses of Arabidopsis to Waterlogging Stress, María Ángeles Peláez-Vico, Adama Tukuli, Pallav Singh, David G. Mendoza-Cózatl, Trupti Joshi, and Ron Mittler
De Novo Transcriptome Assembly from the Nodal Root Growth Zone of Hydrated and Water-Deficit Stressed Maize Inbred Line FR697, Sidharth Sen, Shannon K. King, Tyler McCubbin, Laura A. Greeley, Rachel A. Mertz, Cheyenne Becker, Nicole Niehues, Shuai Zeng, Jonathan T. Stemmle, Scott C. Peck, Melvin J. Oliver, Felix B. Fritschi, David M. Braun, Robert E. Sharp, and Trupti Joshi
The Transcriptome of Soybean Reproductive Tissues Subjected to Water Deficit, Heat Stress and a Combination of Water Deficit and Heat Stress, Ranjita Sinha, Sai Preethi Induri, María Ángeles Peláez-Vico, Adama Tukuli, Benjamin Shostak, Sara I. Zandalinas, Trupti Joshi, Felix B. Fritschi, and Ron Mittler
The Effects of Multifactorial Stress Combination on Rice and Maize, Ranjita Sinha, María Ángeles Peláez-Vico, Benjamin Shostak, Thao Thi Nguyen, Lidia S. Pascual, Andrew M. Ogden, Zhen Lyu, Sara I. Zandalinas, Trupti Joshi, Felix B. Fritschi, and Ron Mittler
A novel role of TGFBI in macrophage polarization and macrophage-induced pancreatic cancer growth and therapeutic resistance, Jing Zhou, Nan Lyu, Qiongling Wanga, Ming Yang, Eric T. Kimchi, Kun Chenge, Trupti Joshi, Adama R. Tukulif, Kevin F. Staveley-O’Carroll, and Guangfu Li
Submissions from 2022
Effect of umbilical cord essential and toxic elements, thyroid levels, and Vitamin D on childhood development, Jesse Cottrell, Chelsea Nelson, Catherine Waldron, Mackenzie Bergeron, Abigail Samson, and Monica Valentovic
Spherical Invasion Assay: A Novel Method to Measure Invasion of Cancer Cells, Stephen D. Richbart, Justin Merritt, Emily G. Moles, Kathleen C. Brown, Adeoluwa A. Adeluola, Paul T. Finch, Joshua A. Hess, Maria T. Tirona, Sarah Miles, Monica Valentovic, and Piyali Dasgupta
The Effects of Rosiglitazone on Task Specific Anxiety-Like Behavior and Novelty Seeking in a Model of Chronic Adolescent Unpredictable Stress, Hannah Sexton, Nathan A. Olszewski, and Mary-Louise Risher
Diverging Effects of Adolescent Ethanol Exposure on Tripartite Synaptic Development across Prefrontal Cortex Subregions, Christopher Douglas Walker, Hannah Gray Sexton, Jentre Hyde, Brittani Greene, and Mary-Louise Risher
Submissions from 2021
Alterations in excitatory and inhibitory synaptic development within the mesolimbic dopamine pathway in a mouse model of prenatal drug exposure, Taylor Boggess, James C. Williamson, Ethan B. Niebergall, Hannah Sexton, Richard D. Egleton, Larry Grover, and Chris Risher
Astrocyte-Derived Thrombospondin Induces Cortical Synaptogenesis in a Sex-Specific Manner, Anna Mazur, Ean H. Bills, Kayla M. DeSchepper, James C. Williams, Brandon J. Henderson, and W. Christopher Risher
Genes causing congenital hydrocephalus: Their chromosomal characteristics of telomere proximity and DNA compositions, Ian McKnight, Christoph Hart, In-Hyun Park, and Joon W. Shim
Nonpungent N-AVAM Capsaicin Analogues and Cancer Therapy, Stephen Richbart, Jamie R. Friedman, Kathleen C. Brown, Rama S. Gadepalli, Sarah L. Miles, John M. Rimoldi, Gary O. Rankin, Monica Valentovic, Maria T. Tirona, Paul T. Finch, Joshua Hess, and Piyali Dasgupta
Submissions from 2020
Genetic and epigenetic determinants of diffuse large B-cell lymphoma, Tanner Bakhshi and Philippe T. Georgel
Clinical and basic research investigations into the long‐term effects of prenatal opioid exposure on brain development, Taylor Boggess and W. Chris Risher
Emerging roles for α2δ subunits in calcium channel function and synaptic connectivity, William Christopher Risher and Cagla Eroglu
Generation of In-Frame Gene Deletion Mutants in Pseudomonas aeruginosa and Testing for Virulence Attenuation in a Simple Mouse Model of Infection, Meagan E. Valentine, Brandon D. Kirby, and Hongwei D. Yu
Regulation of synaptic development by astrocyte signaling factors and their emerging roles in substance abuse, Christopher D. Walker, W. Chris Risher, and Mary-Louise Risher
Submissions from 2018
Pyrimidine biosynthesis regulates the small colony variant and mucoidy in Pseudomonas aeruginosa through sigma factor competition, Roy Al Ahmar, Brandon D. Kirby, and Hongwei Yu
Epidermal growth factor (EGF) autocrine activation of human platelets promotes EGF receptor-dependent oral squamous cell carcinoma cell invasion, migration, and epithelial mesenchymal transition, Rui Chen, Ge Jin, Wei Li, and Thomas M. McIntyre
Paraoxonase 2 prevents the development of heart failure, Wei Li
Thymidine phosphorylase: A potential new target for treating cardiovascular disease, Wei Li and Hong Yue
Thrombospondin receptor α2δ-1 promotes synaptogenesis and spinogenesis via postsynaptic Rac1, W. Chris Risher, Namsoo Kim, Sehwon Koh, Ji‑Eun Cho, Petar Mitev, Erin F. Spence, Louis‑Jan Pilaz, Dongqing Wang, Guoping Feng, Debra L. Silver, Scott H. Soderling, Henry H. Yin, and Cagla Eroglu
CD36 Enhances Vascular Smooth Muscle Cell Proliferation and Development of Neointimal Hyperplasia, Hong Yue, Maria Febbraio, Philip A. Klenotic, David J. Kennedy, Yueheng Wu, Shaoxian Chen, Amira F. Gohara, Oliver Li, Adam Belcher, Bin Kuang, Thomas M. McIntyre, Roy L. Silverstein, and Wei Li
Submissions from 2017
Tell-tale SNPs: The role of CYP2B6 in methadone fatalities, Taha Ahmad, Samie Sabet, Donald A. Primerano, Lauren L. Richards-Waugh, and Gary O. Rankin
Platelet microparticle-inspired clot-responsive nanomedicine for targeted fibrinolysis, Christa L. Pawlowski, Wei Li, Michael Sun, Kavya Ravichandran, DaShawn Hickman, Clarissa Kos, Gurbani Kaur, and Anirban Sen Gupta
In vitro characterization of SynthoPlateTM (synthetic platelet) technology and its in vivo evaluation in severely thrombocytopenic mice, Meenal Shukla, Ujjal D. S. Sekhon, Venkaiah Betapudi, Wei Li, D. A. Hickman, Christa L. Pawlowski, Mitchell R. Dyer, Matthew D. Neal, Keith R. McCrae, and A. Sen Gupta
Platelet CD36 promotes thrombosis by activating redox sensor ERK5 in hyperlipidemic conditions, Moua Yang, Brian C. Cooley, Wei Li, Yiliang Chen, Jeannette Vasquez-Vivar, Na’il O. Scoggins, and Scott J. Cameron
Submissions from 2016
Changes in the Adult GluN2B Associated Proteome following Adolescent Intermittent Ethanol Exposure, H. Scott Swartzwelder, Mary-Louise Risher, Kelsey M. Miller, Roger J. Colban, Danner G. Winder, and Tiffany A. Wills
Submissions from 2015
Deubiquitinases modulate platelet proteome ubiquitination, aggregation, and thrombosis., Nilaksh Gupta, Wei Li, and Thomas M. McIntyre
Platelet-activating factor receptor affects food intake and body weight, Wei Li and Thomas M. McIntyre
Adolescent Intermittent Alcohol Exposure: Dysregulation of Thrombospondins and Synapse Formation are Associated with Decreased Neuronal Density in the Adult Hippocampus, Mary-Louise Risher, Hannah G. Sexton, W. Christopher Risher, Wilkie A. Wilson, Rebekah L. Fleming, Roger D. Madison, Scott D. Moore, Cagla Eroglu, and H. Scott Swartzwelder
Adolescent Intermittent Alcohol Exposure: Deficits in Object Recognition Memory and Forebrain Cholinergic Markers, H. Scott Swartzwelder, Shawn K. Acheson, Kelsey M. Miller, Hannah G. Sexton, Wen Liu, Fulton T. Crews, and Mary-Louise Risher
The SOX9 upstream region prone to chromosomal aberrations causing campomelic dysplasia contains multiple cartilage enhancers, Baojin Yao, Qiuqing Wang, Chia-Feng Liu, Pallavi Bhattaram, Wei Li, Timothy J. Mead, James F. Crish, and Véronique Lefebvre
Submissions from 2014
Regional-Specific Effects of Ovarian Hormone Loss on Synaptic Plasticity in Adult Human APOE Targeted Replacement Mice, Rebecca C. Klein, Shyla Saini, Mary-Louise Risher, Shawn K. Acheson, Rebekah L. Fleming, Hannah G. Sexton, H. Scott Swartzwelder, and Scott D. Moore
Thymidine phosphorylase participates in platelet signaling and promotes thrombosis, Wei Li, Alba Gigante, Maria-Jesus Perez-Perez, Hong Yue, Michio Hirano, Thomas M. McIntyre, and Roy L. Silverstein
Exosome poly‐ubiquitin inhibits platelet activation, downregulates CD 36 and inhibits pro‐atherothombotic cellular functions, Sowmya Srikanthan, Wei Li, Roy L. Silverstein, and Thomas M. McIntyre
Effect of sub-chronic intermittent ethanol exposure on spatial learning and ethanol sensitivity in adolescent and adult rats, H. S. Swartzwelder, A. Hogan, Mary-Louise Risher PhD, Rita A. Swartzelder, Wilkie A. Wilson, and Shawn K. Acheson
Submissions from 2013
Effects of Acute or Chronic Ethanol Exposure during Adolescence on Behavioral Inhibition and Efficiency in a Modified Water Maze Task, Shawn K. Acheson, Craig Bearison, Mary-Louise Risher, Sabri H. Abdelwahab, Wilkie A. Wilson, and H. Scott Swartzwelder
Binge-pattern ethanol exposure during adolescence, but not adulthood, causes persistent changes in GABAA receptor-mediated tonic inhibition in dentate granule cells, Rebekah L. Fleming, Qiang Li, Mary-Louise Risher, Hannah G. Sexton, Scott D. Moore, Wilkie A. Wilson, Shawn K. Acheson, and H. Scott Swartzwelder
Long-term modulation of A-type K+ conductances in hippocampal CA1 interneurons in rats after chronic intermittent ethanol exposure during adolescence or adulthood, Qiang Li, Rebekah L. Fleming, Shawn K. Acheson, Roger D. Madison, Scott D. Moore, Mary-Louise Risher, Wilkie A. Wilson, and H. S. Swarztwelder
Long-Term Effects of Chronic Intermittent Ethanol Exposure in Adolescent and Adult Rats: Radial-Arm Maze Performance and Operant Food Reinforced Responding, Mary-Louise Risher, Rebekah L. Fleming, Nathalie Boutros, Svetlana Semenova, Wilkie A. Wilson, Edward D. Levin, Athina Markou, H. Scott Swartzwelder, and Shawn K. Acheson
Submissions from 2012
Effects of ethanol, Δ(9)-tetrahydrocannabinol, or their combination on object recognition memory and object preference in adolescent and adult male rats, Nicholas A. Swartzwelder, Mary-Louise Risher, Sabri H. Abdelwahab, Anouska D'Abo, Amir H. Rezvani, Edward D. Levin, Wilkie A. Wilson, h. Scott Swartzwelder, and Shawn K. Acheson
Submissions from 2010
Repeated exposures to low-level chlorpyrifos results in impairments in sustained attention and increased impulsivity in rats, Mary-Louise Risher, Buccafusco J. J., and A. V. Terry Jr.
Repeated, intermittent exposures to diisopropylfluorophosphate in rats: protracted effects on cholinergic markers, nerve growth factor-related proteins, and cognitive function, Alvin V. Terry Jr., Jerry J. Buccafusco, Debra A. Gearhart, Wayne D. Beck, and Mary-Louise Risher
Submissions from 2007
Increased hemorrhagic transformation and altered infarct size and localization after experimental stroke in a rat model type 2 diabetes, Adviye Ergul, Mostafa M. Elgebaly, Mary-Louise Risher, Weiguo Li, Hazem Elewa, Jeffrey A. Switzer, Christiana Hall, Anna Kozak, and Susan C. Fagan
Oral haloperidol or risperidone treatment in rats: temporal effects on nerve growth factor receptors, cholinergic neurons, and memory performance, Alvin V. Terry Jr., Debra A. Gearhart, Samantha E. Warner, Guidong Zhang, Michael G. Bartlett, and Mary-Louise Risher
Protracted effects of chronic oral haloperidol and risperidone on nerve growth factor, cholinergic neurons, and spatial reference learning in rats, A V. Terry Jr., D. A. Gearheart, S. Warner, E. J. Hohnadel, Mary-Louise Risher, G. Zhang, M. G. Bartlett, and S. P. Mahadik
