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Research from 2012

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High-Fat Diet Exacerbates Renal Dysfunction in SHR: Reversal by Induction of HO-1–Adiponectin Axis, Jian Cao, Kazuyoshi Inoue, Komal Sodhi, Nitin Puri, Stephen J. Peterson, Rita Rezzani, and Nader G. Abraham

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Heme Oxygenase Gene Targeting to Adipocytes Attenuates Adiposity and Vascular Dysfunction in Mice Fed a High-Fat Diet, Jian Cao, Stephen J. Peterson, Komal Sodhi, Luca Vanella, Ignazio Barbagallo, Luigi F. Rodella, Michal L. Schwartzman, Nader G. Abraham, and Attallah Kappas

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Apo A1 Mimetic Rescues the Diabetic Phenotype of HO-2 Knockout Mice via an Increase in HO-1 Adiponectin and LKBI Signaling Pathway, Jian Cao, Nitin Puri, Komal Sodhi, Lars Bellner, Nader G. Abraham, and Attallah Kappas

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Down-regulation of the transcription factor snail in the placentas of patients with preeclampsia and in a rat model of preeclampsia, Larissa Federova, Cara Gatto-Weis, Sleiman Smaili, Nauman Khurshid, Joseph I. Shapiro M.D., Deepak Malhorta, and Terrence Horrigan

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Monoclonal antibody against marinobufagenin reverses cardiac fibrosis in rats with chronic renal failure, Steven T. Haller, David J. Kennedy, Amjad Shidyak, George V. Bundy, Deepak Malhorta, Olga V. Fedorova, Joseph I. Shapiro M.D., and Alexi Y. Bagrov

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Higher-Level Production of Volatile Fatty Acids In Vitro by Chicken Gut Microbiotas than by Human Gut Microbiotas as Determined by Functional Analyses, Fang Lei, Yeshi Yin, Yuezhu Wang, Bo Deng, Hongwei David Yu, Lanjuan Li, Charlie Xiang, Shengyue Wang, Baoli Zhu, and Xin Wang

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Colonization and Distribution of Segmented Filamentous Bacteria (SFB) in Chicken Gastrointestinal Tract and Their Relationship with Host Immunity, Ningbo Liao, Yeshi Yin, Guochang Sun, Charlie Xiang, Donghong Liu, Hongwei D. Yu, and Xin Wang

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Stem Cell Transplantation Increases Antioxidant Effects in Diabetic Mice, Ming Li, Luca Vanella, Yuming Zhang, Ming Shi, Takashi Takaki, Joseph I. Shapiro M.D., and Susuma Ikehera

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Reduction of Na/K-ATPase potentiates marinobufagenin-induced cardiac dysfunction and myocyte apoptosis, Changxuan Liu, Yan Bai, Yiliang Chen, Yu Wang, Yoann Sottejeau, Lijun Liu, Xiaomei Li, Jerry B. Lingrel, Deepak Malhorta, Christopher Cooper, Joseph I. Shapiro M.D., Zi-jian Xie, and Jiang Tian

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In preeclampsia, endogenous cardiotonic steroids induce vascular fibrosis and impair relaxation of umbilical arteries, Elena R. Nikitina, Anton V. Mikhailov, Ekaterina S. Nikandrova, Elena V. Frolova, Artem V. Fadeev, Vera V. Shman, Victoria Y. Shilova, Natalia I. Tapilskaya, Joseph I. Shapiro M.D., Olga V. Fedorova, and Alexei Y. Bagrov

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Heme Induced Oxidative Stress Attenuates Sirtuin1 and Enhances Adipogenesis in Mesenchymal Stem Cells and Mouse Pre-Adipocytes, Nitin Puri, Komal Sodhi, Michael Haarstad, Dong Hyun Kim, Steven Bohinc, Eleonora Foglio, Gaia Favero, and Nader G. Abraham

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Expression of Heme Oxygenase-1 in Thick Ascending Loop of Henle Attenuates Angiotensin II-Dependent Hypertension, David E. Stec, Heather A. Drummond, Moneete U. Gousette, Megan V. Storm, Nader G. Abraham, and Eva Csongradi

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Apolipoprotein A-I mimetic peptide L-4F prevents myocardial and coronary dysfunction in diabetic mice, C. Vecoli, J. Cao, D. Neglia, K. Inoue, Komal Sodhi, L. Vanella, K. K. Gabrielson, D. Bedja, N. Paolocci, A. L'Abbate, and Nader G. Abraham

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Draft Genome Sequence for Pseudomonas aeruginosa Strain PAO579, a Mucoid Derivative of PAO381, T. Ryan Withers, Shannon L. Johnson, and Hongwei D. Yu

Research from 2011

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Mechanism of Heme-Heme Oxygenase System Impairment of Endothelium Contraction in the Spontaneously Hypertensive Rat, Nader G. Abraham and Attallah Kappas

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YBX1 Expression and Function in Early Hematopoiesis and Leukemic Cells, Jasjeet Bhullar and Vincent E. Sollars

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Lentiviral-human heme oxygenase targeting endothelium improved vascular function in angiotensin II animal model of hypertension., J. Cao, Komal Sodhi, K. Inoue, J. Quilley, R. Rezzani, L. Vanella, L. Germinario, D. E. Stec, and A. Kappas

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Vanadate and triclosan synergistically induce alginate production by Pseudomonas aeruginosa strain PAO1, F. Heath Damron, Michael R. Davis Jr., T. Ryan Withers, Robert K. Ernst, Joanna B. Goldberg, Guangli Yu, and Hongwei D. Yu

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Analysis of the Pseudomonas aeruginosa regulon controlled by the sensor kinase KinB and sigma factor RpoN, F. Heath Damron, Joshua P. Owings, Yuta Okkotsu, John J. Varga, Jill R. Schurr, Joanna B. Goldberg, Michael J. Schurr, and Hongwei D. Yu

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Pseudomonas aeruginosa MucD Regulates the alginate Pathway through Activation of MucA Degradation via MucP Proteolytic Activity, F. Heath Damron and Hongwei D. Yu

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Joining the conversation: Predictors of success on the United States Medical Licensing Examinations (USMLE), Sabry Gohara, Joseph I. Shapiro MD, Adam N. Jacob, Sadik A. Khuder, Robyn A. Gandy, Patricia J. Metting, Jeffrey Gold, and James Kleshinkski

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Platelet Activation in Patients with Atherosclerotic Renal Artery Stenosis Undergoing Stent RevascularizationPlatelet Activation in Patients with Atherosclerotic Renal Artery Stenosis Undergoing Stent Revascularization, Steven Haller, Satjit Adlakha, Grant Reed, Pamela Brewster, David Kennedy, Mark W. Burket, William Colyer, Haifeng Yu, Dong Zhang, Joseph I. Shapiro M.D., and Christopher J. Cooper

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Dietary Walnut Suppressed Mammary Gland Tumorigenesis in the C(3)1 TAg Mouse, W. Elaine Hardman

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Effects of Canola and Corn Oil Mimetic on Jurkat Cells, Gabriela Ion, Kayla Fazio, Juliana A. Akinsete, and W. Elaine Hardman

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Reciprocal Effects of Oxidative Stress on Heme Oxygenase Expression and Activity Contributes to Reno-Vascular Abnormalities in EC-SOD Knockout Mice, Tomoko Kawakami, Nitin Puri, Komal Sodhi, Lars Bellner, Toru Takahashi, Kiyoshi Morita, Rita Rezzani, Tim D. Oury, and Nader G. Abraham

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Dysglycemia induces abnormal circadian blood pressure variability, Sivarajan Kumarasamy, Kathirvel Gopalakrishnan, Dong Hyun Kim, Nader G. Abraham, William D. Johnson, Bina Joe, and Alok K. Gupta

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Na/K-ATPase mimetic pNaKtide Peptide inhibits the growth of human cancer cells, Zhichuan Li, Zhongbing Zhang, Joe X. Xie, Xin Li, Jiang Tian, Ting Cai, Hongaun Cui, Hanfei Ding, Joseph I. Shapiro MD, and Zijian Xie

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Structural basis for the interaction of the free SH2 domain EAT‐2 with SLAM receptors in hematopoietic cells, Massimo Morra, Jun Lu, Florence Poy, Margarita Martin, Joan Sayos, Silvia Calpe, Charles A. Gullo PhD, Duncan Howie, Svend Rietdijk, Andrew Thompson, Anthony J. Coyle, Christopher Denny, Michael B. Yaffe, Pablo Engel, Michael J. Eck, and Cox Terhorst

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EET agonist prevents adiposity and vascular dysfunction in rats fed a high fat diet via a decrease in Bach 1 and an increase in HO-1 levels, Komal Sodhi, Nitin Puri, Kazuyoshi Inoue, John R. Falck, Michal L. Schwartzman, and Nader G. Abraham

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Oxidative Stress and Heme Oxygenase-1 Regulated Human Mesenchymal Stem Cells Differentiation, Luca Vanella, Christopher Sanford Jr., Dong Hyun Kim, Nader G. Abraham, and Nabil Ebraheim

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A High Omega-3 Fatty Acid Diet has Different Effects on Early and Late Stage Myeloid Progenitors, Melinda E. Varney, James T. Buchanan, Yulia Dementieva, W. Elaine Hardman, and Vincent E. Sollars

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Domain Requirements for the Diverse Immune Regulatory Functions of Foxp3, Wei-ping Zeng, Vincent E. Sollars, and Andrea Del Pilar Belalcazar

Research from 2010

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Overexpression of heme oxygenase-1 increases human osteoblast stem cell differentiation, Ignazio Barbagallo, Angelo Vanella, Stephen J. Peterson, Dong Hyun Kim, Daniele Tibullo, Cesarina Giallongo, Luca Vanella, Nunziatina Parrinello, Giuseppe A. Palumbo, Francesco Di Raimondo, Nader G. Abraham, and David Asprinio

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Capsaicin Displays Anti-Proliferative Activity against Human Small Cell Lung Cancer in Cell Culture and Nude Mice Models via the E2F Pathway, Kathleen C. Brown, Theodore R. Witte, W. Elaine Hardman, Haitao Luo, Yi C. Chen, A. Betts Carpenter, Jamie K. Lau, and Piyali Dasgupta

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Adipocyte Heme Oxygenase-1 Induction Attenuates Metabolic Syndrome in Both Male and Female Obese Mice, Angela Burgess, Ming Li, Luca Vanella, Dong Hyun Kim, Rita Rezzani, Luigi Rodella, Komal Sodhi, Martina Canestraro, Pavel Martasek, Stephen J. Peterson, Attallah Kappas, and Nader G. Abraham

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Silencing and Re-Expression of Retinoic Acid Receptor Beta2 in Human Melanoma, Jun Fan, Linda L. Eastham, Melinda E. Varney, Adam Hall, Nicolas L. Adkins, Vincent E. Sollars, Philippe T. Georgel, and Richard M. Niles

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Expression and Function of CD9 in Melanoma Cells, Jun Fan, Guo-Zhang Zhu, and Richard M. Niles

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Eradication of Therapy-resistant Human Prostate Tumors Using an Ultrasound-guided Site-specific Cancer Terminator Virus Delivery Approach, Adelaide Greco, Altomare Di Benedetto, Candace M. Howard, Sarah Kelly, Rounak Nande, Yulia Dementieva, Michele Miranda, Arturo Brunetti, Marco Salvatore, Luigi Claudio, Devanand Sarkar, Paul Dent, David T. Curiel, Paul B. Fisher, and Pier P. Claudio

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Inhibition of Proliferation and Induction of Apoptosis in Multiple Myeloma Cell Lines by CD137 Ligand Signaling, Charles A. Gullo PhD, Liang Kai Koh, Wan Lu Pang, Kian Tong Ho, Shi Hao Tan, and Herbert Schwarz

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Maternal Consumption of Canola Oil Suppressed Mammary Gland Tumorigenesis in C3(1) TAg Mice Offspring, Gabriela Ion, Juliana A. Akinsete, and W. Elaine Hardman

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Prieurianin Causes Weight Loss in Diet-Induced Obese Mice and Inhibits Adipogenesis in Cultured Preadipocytes, Ahmed Kablan, Rudel A. Saunders, Maria Szkudlarek-Mikho, Andrew J.B. Chin, Raul M. Bosio, Kazuyuki Fujii, Joseph I. Shapiro M.D., and Khew-Voon Chin

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Rapid Selection and Proliferation of CD133(+) Cells from Cancer Cell Lines: Chemotherapeutic Implications, Sarah E. Kelly, Altomare Di Benedetto, Adelaide Greco, Candace M. Howard, Vincent E. Sollars, Donald A. Primerano, Jagan V. Valluri, and Pier P. Claudio

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Epoxyeicosatrienoic Acid Agonist Regulates Human Mesenchymal Stem Cell–Derived Adipocytes Through Activation of HO-1-pAKT Signaling and a Decrease in PPARγ, Dong Hyun Kim, Luca Vanella, Kazuyoshi Inoue, Angela Burgess, Katherine Gotlinger, Vijaya Lingam Manthati, Sreenivasulu Reddy Koduru, Darryl C. Zeldin, John R. Falck, Michal L. Schwartzman, and Nader G. Abraham

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Improved Myocardial Perfusion in Chronic Diabetic Mice by the Up-Regulation of pLKB1 and AMPK Signaling, Claudia Kusmic, Antonio L'Abbate, Gianmario Sambuceti, George Drummond, Cristina Barsanti, Marco Matteucci, Jian Cao, Francesco Piccolomini, Jennifer Cheng, and Nader G. Abraham

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Usefulness of Clopidogrel to Protect Against Diabetes-Induced Vascular Damage, John A. McClung MD, Adam L. Kruger DO, Ambra Ferraris MD, Luca Vanella PhD, Petr Tsenovoy MD, Melvin B. Weiss MD, and Nader G. Abraham PhD

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17-N-Allylamino-17-Demethoxygeldanamycin Induces a Diverse Response in Human Acute Myelogenous Cells, Jennifer M. Napper and Vincent E. Sollars

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CYP4A2-Induced Hypertension Is 20-Hydroxyeicosatetraenoic Acid– and Angiotensin II–Dependent, Komal Sodhi, Cheng-Chia Wu, Jennifer Cheng, Katherine Gotlinger, Kazuyoshi Inoue, Mohan Goli, John R. Falck, Nader G. Abraham, and Michal L. Schwartzman

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Renal Ischemia Regulates Marinobufagenin Release in Humans, Jiang Tian, Steven Haller, Sankaridrug Periyasamy, Pamela Brewster, Haifeng Zhang, Satjit Adlakha, Olga V. Fedorova, Zi-jian Xie, Alexei Y. Bagrov, Joseph I. Shapiro M.D., and Christopher J. Cooper

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HO-1 expression increases mesenchymal stem cell-derived osteoblasts but decreases adipocyte lineage, Luca Vanella, Dong Hyun Kim, David Aspirino, Stephen J. Peterson, Ignazio Barbagallo, Angelo Vanella, Dove Goldstien, Susumu Ikehara, and Nader G. Abraham

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RBC and WBC Fatty Acid Composition Following Consumption of an omega 3 Supplement: Lessons for Future Clinical Trials, Theodore R. Witte, Alexander J. Salazar, Oscar F. Ballester, and W. Elaine Hardman

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Identification of Hydroxyxanthones as Na/K-ATPase Ligands, Zhongbing Zhang, Zhichuan Li, Jiang Tian, Wei Jiang, Yin Wang, Xiaojin Zhang, Zhuorong Li, Qidong You, Joseph I. Shapiro M.D., Shuyi Si, and Zijian Xie

Research from 2009

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The Krebs Cycle and Mitochondrial Mass Are Early Victims of Endothelial Dysfunction : Proteomic Approach, Francesco Addabbo, Brian Ratliff, Hyeong-Cheon Park, Mei-Chuan Kuo, Zoltan Ungvari, Anna Ciszar, and Boris Krasnikof

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Susceptibility to Autoimmunity and B Cell Resistance to Apoptosis in Mice Lacking Androgen Receptor in B Cells, Saleh Altuwaijri, Kuang-Hsiang Chuang, Kuo-Pao Lai, Jiann-Jyh Lai, Hung-Yun Lin, Faith M. Young, Andrea Bottaro, Meng-Yin Tsai, Wei-Ping Zeng, Hong-Chiang Chang, Shuyuan Yeh, and Chawnshang Chang

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Lipotoxin F of Pseudomonas aeruginosa is an AlgU-dependent and alginate-independent outer membrane protein involved in resistance to oxidative stress and adhesion to A549 human lung epithelia, F. Heath Damron, Jennifer Napper, M. Allison Teter, and Hongwei D. Yu

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The Probiotic Content of Commercial Yogurts in West Virginia, Brian S. Dunlap, Hongwei Yu, and Yoram Elitsur

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Marinobufagenin induces increases in procollagen expression in a process involving protein kinase C and Fli-1: implications for uremic cardiomyopathy, Jihad Elkareh, Sankaridrug M. Periyasamy, Amjad Shidyak, Sandeep Vetteth, Jeremy Schroeder, Vanamala Raju, Imad M. Hariri, Nasser El-Okdi, Shalini Gupta, Larisa Fedorova, Jiang Liu, Olga V. Fedorova, M. Bashar Kahaleh, Zijian Xie, Deepak Malhotra, Dennis K. Watson, Alexei Y. Bagrov, and Joseph I. Shapiro M.D.

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The cardiotonic steroid hormone marinobufagenin induces renal fibrosis: implication of epithelial-to-mesenchymal transition, Larisa V. Fedorova, Vanamala Raju, Nasser El-Okdi, Amjad Shidyak, David J. Kennedy, Sandeep Vetteth, David R. Giovannucci, Alexei Y. Bagrov, Olga V. Fedorova, Joseph I. Shapiro M.D., and Deepak Malhorta

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Endothelial-specific CYP4A2 overexpression leads to renal injury and hypertension via increased production of 20-HETE, Kazuyoshi Inoue, Komal Sodhi, Nitin Puri, Katherine H. Gotlinger, Jiang Cao, Rita Rezzani, John R. Falck, Nader G. Abraham, and Michal Laniado-Schwartzman

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Use of Phage Display to Isolate Specifi c Human Monoclonal Antibody Fragments Against a Potential Target for Multiple Myeloma, Pei Xiong Liew, Feng Ge, Charles A. Gullo, Gerrard KH Teoh, and William YK Hwang

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Epocrates….Is It Useful at the Neonatal Bedside?, Bobby L. Miller MD

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Expression and Function of Hypoxia Inducible Factor-1 Alpha in Human Melanoma Under Non-hypoxic Conditions, Caroline N. Mills, Sandeep S. Joshi, and Richard M. Niles

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Investigating the effect of genetic background on proteinuria and renal injury using two hypertensive strain, Matthew Packard, Yasser Saad, William T. Gunning, Shalini Gupta, Joseph I. Shapiro M.D., and Michael R. Garrett

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Body and Disease 2008: An Integrated Course Teaching Pathology, Pharmacology, Immunology and Microbiology, Janil Puthucheary, Doyle Graham, Charles A. Gullo Phd, Hwang Nina Chih, Lynette Oon, Tan Soo Yong, and Sandy Cook

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The Mycoplasma genitalium MG_454 Gene Product Resists Killing by Organic Hydroperoxides, Sankaralingam Saikolappan, Smitha J. Sasindran, Hongwei D. Yu, Joel B. Basema, and Subramanian Dhandayuthapani

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Epoxyeicosatrienoic Acid Agonist Rescues the Metabolic Syndrome Phenotype of HO-2-Null Mice, Komal Sodhi, Kazuyoshi Inoue, Katherine H. Gotlinger, Martina Canestraro, Luca Vanella, Dong Hyun Kim, Vijay L. Manthati, Sreenivasulu Reddy Koduru, John R. Falck, Michal L. Schwartzman, and Nader G. Abraham

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Spironolactone Attenuates Experimental Uremic Cardiomyopathy by Antagonizing Marinobufagenin, Jiang Tian, Amjad Shidyak, Sankaridrug M. Periyasamy, Steven Haller, Mohamed Taleb, Nasser El-Okdi, Jihad Elkareh, Shalini Gupta, Sabry Gohara, Olga V. Fedorova, Christopher J. Cooper, Zijian Xie, Deepak Malhorta, Alexei Y. Bagrov, and Joseph I. Shapiro M.D.

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Omega 3 fatty acids reduce myeloid progenitor cell frequency in the bone marrow of mice and promote progenitor cell differentiation, Melinda E. Varney, W. Elaine Hardman, and Vincent E. Sollars

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The Pseudomonas aeruginosa sensor kinase KinB negatively controls alginate production through AlgW-dependent MucA proteolysis, Hongwei D. Yu, F. Heath Damron, and Dongru Qiu

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Immune Suppressive Activity and Lack of T Helper Differentiation Are Differentially Regulated in Natural Regulatory T Cells, Wei-ping Zeng, Chawnshang Chang, and Jiann-jyh Lai

Research from 2008

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PPARα/γ Expression and Activity in Mouse and Human Melanocytes and Melanoma Cells, Linda L. Eastham, Caroline N. Mills, and Richard M. Niles

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Effects of cardiotonic steroids on dermal collagen synthesis and wound healing, Nasser El-Okdi, Sleiman Smaili, Vanamala Raju, Amjad Shidyak, Shalini Gupta, Larisa Fedorova, Jihad Elkareh, Sankaridrug Periyasamy, Anna P. Shapiro, M. Bashar Kahaleh, Deepak Malhotra, Jingwei Xie, Khew Voon Chin, and Joseph I. Shapiro M.D.

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Global Analysis of Gene Expression Changes During Retinoic Acid-Induced Growth Arrest and Differentiation of Melanoma: Comparison to Differentially Expressed Genes in Melanocytes vs Melanoma, Mary H. Estler, Goran Boskovic, James Denvir, Sarah Miles, Donald A. Primerano, and Richard M. Niles

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Ku86 exists as both a full-length and a protease-sensitive natural variant in multiple myeloma cells, Charles A. Gullo PhD, Feng Ge, Geraline Cow, and Gerrard Teoh

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Use of Ultraviolet Light Irradiated Multiple Myeloma Cells as Immunogens to generate Tumor Specific Cytolytic T Lymphocytes, Charles A. Gullo PhD, William Y.K. Hwang, Chye K. Poh, Melvin Au, Geraline Cow, and Gerrard Teoh

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Association of Epstein-Barr virus with nasopharyngeal carcinoma and current status of development of cancer-derived cell lines, Charles A. Gullo PhD, Wong Kein Low, and Gerrard Teoh

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Suppression of Implanted MDA-MB 231 Human Breast Cancer Growth in Nude Mice by Dietary Walnut, W. Elaine Hardman and Gabriela Ion

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Retinoic Acid Decreases ATF-2 Phosphorylation and Sensitizes Melanoma Cells to Taxol-Mediated Growth Inhibition, Ying Huang, Jennifer Minigh, Sarah Miles, and Richard N. Niles

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PBAD-based shuttle vectors for functional analysis of toxic and highly regulated genes in Pseudomonas and Burkholderia spp. and other bacteria, Dongru Qiu, F. Heath Damron, Takehiko Mima, Herbert P. Schweizer, and Hongwei D. Yu

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ClpXP proteases positively regulate alginate overexpression and mucoid conversion in Pseudomonas aeruginosa, Dongru Qiu, Vonya M. Eisinger, Nathan E. Head, Gerald B. Pier, and Hongwei D. Yu

Research from 2007

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Temporal and Spatial Changes of Histone 3 K4 Dimethylation at the IFN-γ Gene during Th1 and Th2 Cell Differentiation, Heli K. Hamalainen-Laanaya, James J. Kobie, Chawnshang Chang, and Wei-ping Zeng

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Dietary Canola Oil Suppressed Growth of Implanted MDA-MB 231 Human Breast Tumors in Nude Mice, W. Elaine Hardman

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Identification of a pool of non-pumping Na/K-ATPase, Man Liang, Jiang Tian, Lijun Liu, Sandrine Pierre PhD, Jiang Liu, Joseph I. Shapiro M.D., and Zi-jian Xie

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Biomarker and Animal Models for Assessment of Retinoid Efficacy in Cancer Chemoprevention, Richard M. Niles

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Regulated proteolysis controls mucoid conversion in Pseudomonas aeruginosa, Dongru Qiu, Vonya M. Eisinger, Donald W. Rowen, and Hongwei D. Yu

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Evolution of Enzymatic Activities in the Enolase Superfamily: d-Mannonate Dehydratase from Novosphingobium aromaticivorans, John F. Rakus, Alexander A. Fedorov, Elena V. Federov, Margaret E. Glasner, Jacob E. Vick, Patricia C. Babbitt, Steven C. Almo, and John A. Gerlt

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Divergent Haplotypes and Human History as Revealed in a Worldwide Survey of X-Linked DNA Sequence Variation, Makoto K. Shimada, Karuna Panchapakesan, Sarah A. Tishkoff, Alejandro Q. Nato Jr., and Jody Hey

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Defect in Early Lung Defence Against Pseudomonas aeruginosa in DBA/2 Mice is Associated with Acute Inflammatory Lung Injury and Reduced Bactericidal Activity in Naive Macrophages, Kari R. Wilson,; Jennifer M. Napper,; James Denvir; Vincent E. Sollars; and Hongwei D. Yu

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Pharmacological modulation of cGMP levels by phosphodiesterase 5 inhibitors as a therapeutic strategy for treatment of respiratory pathology in cystic fibrosis., Hongwei D. Yu, Jens F. Poschet, Graham S. Timmons, Jennifer L. Taylor-Cousar, Wojciech Ornatowski, Joseph Fazio, Elizabeth Perkett, Kari R. Wilson, Hugo R. de Jonge, and Vojo Deretic

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Interaction between GATA-3 and the Transcriptional Coregulator Pias1 Is Important for the Regulation of Th2 Immune Responses, Xinyan Zhao, Bo Zheng, Yanfang Huang, Dan Yang, Shoshana Katzman, Chawnshang Chang, Deborah Fowell, and Wei-ping Zeng

Research from 2006

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Numerical Distribution of Lymphoid Nodules in the Human Sigmoid Colon, Rectosigmoidal Junction, Rectum, and Anal Canal, Ivan L. Cameron, James E. Kent, Ron Philo, Christopher J. Barnes, and W. Elaine Hardman

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Marinobufagenin Stimulates Fibroblast Collagen Production and Causes Fibrosis in Experimental Uremic Cardiomyopathy, Jihad Elkareh, David J. Kennedy, Belvadi Yashaswi, Sandeep Vetteth, Amjad Shidyak, Eric G.R. Kim, Sleiman Smaili, Sankaridrug M. Periyasamy, Imad M. Hariri, Larisa Fedorova, Jiang Liu, Liang Wu, M. Bashar Kahaleh, Zijian Xie, Deepak Malhotra, Olga V. Fedorova, Vladimir A. Kashkin, Alexei Y. Bagrov, and Joseph I. Shapiro M.D.

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The biology of Ku and its potential oncogenic role in cancer, Charles A. Gullo PhD, Melvin Au, Ge Feng, and Gerrard KH Teoh

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Non–Contrast-Enhanced Computerized Tomography and Analgesic-Related Kidney Disease: Report of the National Analgesic Nephropathy Study, William L. Henrich, Richard L. Clark, Judith P. Kelly, Vardaman M. Buckalew, Andrew Fenves, William F. Finn, Joseph I. Shapiro M.D., Paul L. Kimmel, Paul Eggers, Larry E. Agodoa, George A. Porter, Samuel Shapiro, Robert Toto, Theresa Anderson, L. Adrienne Cupples, and David W. Kaufman

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Thimerosal Induces Apoptosis in a Neuroblastoma Model via the cJun N-terminal Kinase Pathway, Michelle L. Herdman, Aileen Marcello, Ying Huang, Richard M. Niles, Sanjit Dhar, and Kinsley Kelley Kinningham

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Thimerosal Induces Apoptosis in a Neuroblastoma Model via the cJun N-Terminal Kinase Pathway, Michelle L. Herdman, Aileen Marcelo, Ying Huang, Richard M. Niles, Sanjit Dhar, and Kinsley Kelley Kiningham

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Decoupling of normal CD40/interleukin-4 immunoglobulin heavy chain switch signal leads to genomic instability in SGH-MM5 and RPMI 8226 multiple myeloma cell lines, William Y.K Hwang, Charles A. Gullo PhD, Jie Shen, Chee Kok Poh, S. C. Tham, G. Cow, M. Au, E. W. E. Chan, and G. Teoh

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Ouabain decreases sarco(endo)plasmic reticulum calcium ATPase activity in rat hearts by a process involving protein oxidation, David J. Kennedy, Sandeep Vetteth, Miaorong Xie, Sankaridrug M. Periyasamy, Jingwei Xie, Chi Han, Venkatesha Basrur, Krishna Mutgi, Vladimir Fedorov, Deepak Malhotra, and Joseph I. Shapiro M.D.

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Responsiveness of Naive CD4 T Cells to Polarizing Cytokine Determines the Ratio of Th1 and Th2 Cell Differentiation, Natallia Mikhalkevich, Brian Becknell, Michael A. Caligiuri, Michael D. Bates, Richard Harvey, and Wei-ping Zeng

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Resveratrol Is Rapidly Metabolized in Athymic (Nu/Nu) Mice and Does Not Inhibit Human Melanoma Xenograft Tumor Growth, Richard M. Niles, Carla R. Cook, Gary G. Meadows, Ya-Min Fu, Jerry L. McLaughlin, and Gary O. Rankin

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Analysis of expansion of myeloid progenitors in mice to identify leukemic susceptibility genes, Vincent E. Sollars, Ed Pequignot, Jay L. Rothstein, and Arthur M. Buchberg